Biohybrid Devices Essay Example for Free

Biohybrid Devices Essay Biohybrid devices. Biohybrid devices are implantable medical contraptions that undergo vascularization inside the body before the normal human cells (such as islet cells of Langerhans) can be placed inside them. They provide local immunosuppression that ensures that the normal human cells are not rejected by the host’s immune system or the graft versus host disease (Dorian). Biohybrid devices can be used to prevent diseases such as liver failure and diabetes. For persons at risk of developing type I diabetes mellitus (such as genetically predisposed individuals) or pre-diabetic individuals, their islets cells of Langerhans can be protected by biohybrid devices (Ricchie). These biohybrid devices are designed using nanoencapsulation technology into conformal polymer biomaterials that form a scaffold over the population of islet cells of Langerhans in the endocrine pancreas; thereby preventing the auto-antibodies from accessing the islets cells, and, causing irreversible injury to the cells by auto-immune reactions that ultimately lead to cell death, and, absolute lack of insulin production (Lucy et al). For the pre-diabetic individuals on immunomodulatory medications, the biohybrid scaffold locally concentrates the drug thus increasing its pharmacologic efficiency and reducing its systemic toxicity. The biohybrid scaffold also improves nutrient distribution across the islet cells and reduces stress encountered by the islet cells of Langerhans (Nazek). Liver failure caused by autoimmune hepatitis can be prevented by biohybrid devices, which form an, intricate conformal scaffold on the hepatocytes surface thereby blocking the auto-antibodies from interacting with the hepatocytes, and, causing immune-mediated liver necrosis (Nazek). Oxygen diffusion is critical for hybrid artificial organs because the normal human cells within them require oxygen for aerobic oxidative respiration and reduced oxygen diffusion may cause hypoxia (a form of cell injury) that leads to impaired physiological processes within the cells and ultimately to cell death(Lemburt et al). This necessitates that the biohybrid device be made of optimal design that allows adequate oxygen diffusion and consumption by the normal human cells (Dorian). These designs are based on experimental mathematical models (Provust). The characteristics that influence the rate of oxygen diffusion across the biohybrid device are geometry (for instance, the spherical organoid biohybrid artificial liver [BAL] was observed to consume oxygen at rates that approximate normal hepatocytes oxygen consumption, while, the hollow tube model of BAL consumed oxygen at rates several magnitudes lower than normal hepatocytes), thickness of the biohybrid device(for instance, models of biohybrid blood vessels made up of hollow fiber scaffold exhibited correlation between increasing scaffold wall thickness and reduced oxygen perfusion) and permeability of the biohybrid device surface to oxygen. This oxygen permeability is a function of the intrinsic property of the polymer that is used to construct the scaffolds of the biohybrid device; also, the nanoencapsulation design influences oxygen permeability albeit to a smaller extent (Silvius). There are several differences between intravascular and extra vascular biohybrid devices as explained below. Intravascular biohybrid devices are placed within the large blood vessels where they act as stents, or, they connect several blood vessels thereby acting as a biocompatible immunoprotective shunts; thus, the normal human cells within such devices obtain nourishment directly from the circulating blood. Extravascular biohybrid devices are placed outside the vascular compartment, for example, planar macro-capsules (extravascular devices) are placed in the peritoneal cavity; the normal human cells in these devices depend on diffusion to obtain the necessary nutrients and oxygen. The extravascular devices are easily implantable and retrievable, but, the intravascular devices would need surgery in order to implant or retrieve them (Triavek). The geometry of biohybrid devices affects their efficiency because the normal human cells within them require an appropriate three-dimensional structure that maximizes the effective surface area in order to obtain adequate nutrition, oxygen and eliminate metabolic wastes. Geometry also influences the population of human cells that can be placed inside a biohybrid device. Geometry of biohybrid device also affects the interaction between the device and the human immune system (Nazek).

What Should You Do If Someone Have Been Abused Essay Example for Free

What Should You Do If Someone Have Been Abused Essay If a person does not tell you but you suspect that they are being abused, you need to tell your manager You may want to talk to the person before you contact the relevent authorities. If you do this, bring the subject up sensitively by letting the person know that you are concerned about them and want to support them. Listen to them without being impatient or critical of them or their actions. Letting them talk and share their concerns is very important as it helps them to break the silence and know that they are not on their own. Getting involved does not mean that you have to solve the situation. It can be very difficult supporting someone who is being abused as they may not make the decisions that you think they should. It is important that they make the decisions, not you or anyone else, unless the person does not have the mental capacity to do so, in which case you must act in their best interests. Your support will be important to them as they may have very little confidence and poor self esteem as a result of the abuse. Do not put yourself at risk. Always contact the appropriate person if you are concerned for the person’s immediate safety or if they in immediate danger but you are concerned about them. What should you do if an individual tells you they have been abused? When abuse has taken place you should stay calm and remain none judgmental. Put your own feelings aside and try and not communicate shock, disgust embarrassment or disbelief. You should also be supportive and stay close to the alleged victim immediately after the disclosure to provide some sense of physical security. Assure the individual that they did the rite thing by telling you about what happened. Never tell the alleged victim that you do believe them and ensure the individuals safety. Ensure that the alleged abuser does not have access to the victim and assure the victim will stand by them in the process of getting help. Further more you should seek privacy if possible so the individual is protected from disclosing in public and listen closely if the victim wants to talk but do not ask questions beyond  what is necessary to protect the victim and preserve evidence. You should report this to a senior or manager as soon as you have finished talking and made sure the victim is safe so that the nesscery action can be taken. National policies How to ensure abuse evidence is kept safe. Evidence of abuse must be stored carefully to maintain the quality and integrity of the samples either in a locked room were only certain people have access to if on the computer it must be password locked if hand written it needs to be in a lockable cabinet any Clothing must be stored in an airtight manner. Photographs, as evidence should be printed on archival quality paper and locked away in a safe place. Always remember to sign and date your notes and any other records you have made. Medical professionals such as GP, AE staff, nurses, doctors: they can examine, diagnose treat, they can record this can include photographic evidence. Social Services dept would carry out an assessment of needs, this would include any unpaid carer of individual. Safeguarding Team Police to investigate/prosecute, to work with other agencies, to provide support to victims, to raise awareness of crimes, crime prevention. Care Quality Commission to regulate inspect care providers. CRB, to check an individuals past to see if they have any criminal convictions.

Conflict theory

Conflict theory Abstract With the development of the labeling theory, many researchers found experimentation and data collection easier to finding predictors in criminal behavior. Assuming that criminal behavior is constantly existent, according to Emile Durkheim, it is debatable whether crime is beneficial to society. Despite appeals for controlling crime in specific terms of the Classical School, there are complications in todays society that can effect later generations based on the theory of conflict and control. Since competition, dominance, and control are persistent in an individual’s way of life, their behavior is dictated as such through their social class, but also within the behaviors of those opposing them, causing consistent conflict. This paper will explain conflict theories, the theorists and the variables involved, and the select policy implications that can benefit and cripple society for a more stable living environment. Keyword(s): society, conflict, competition, criminal behavior, control, Quinney Conflict Theory The rich versus the poor. The right versus the wrong. The healthy versus the sick. The righteous versus the evil. What these all have in common there is conflict between them all. Whether created based on social status or by some form of problem within individual lives, conflict resides as a form of power or control over others. In today’s society, communities are overpowered by unfair wages, improper education fees, unjust regulations for jobs, and immoral methods of social prosperity within social classes. This continued with a conflict of employment, where jobs are either available for those who want to work or people complain due for certain demands without placing any effort for them. By placing conflict on certain ideals, the rationale of life is divided further to where dominance and control will deconstruct standards ways of life. Main Idea of Conflict Theory The main idea of the conflict theory is an offshoot of the labeling theory. Conflict theory assumes that the rich or powerful have the upper hand in society their philosophy is that conflict in society is inevitable and resources are in demand, and control over these resources brings about a majority of these conflicts in society (Williams McShane, 2014). Whether the conflict between classes lasts between economic status and social status, the theory gathers the assumption of classes dominating one another for the sole purpose of control within a social hierarchy. Complex or Abstract? The perspective of the conflict theorists would be categorized as complex because of the variety of philosophies within the conflict theory. For example, the pluralist conflict perspective assumes struggles based on various groups by numerous reasons including economic and social status (Williams McShane, 2014). Many problems may occur within one section of groups within a functioning society that may collide with other groups, like budget expenses and manpower for war. These problems emerge at any point through everyday life, and can be deterred. However, it is society that dictates the change to take one course of action or another. As a result, the impeding action from one person can influence another, but also hinder an individual to act against the judgment of one for the benefit of resources or availability of needs and services. Because power is synonymous with resources, the social class structures implies, with conflict, that those who can obtain certain luxuries within the social hierarchy can benefit better than others in a plethora of ways. As a result, competition occurs and conflict resumes through domination and control over the others. What Are We Studying? The interdisciplinary natures of this theory involve the affluent members of society controls the resources in society and uses the law as the way for control. For pluralist conflict perspectives, as stated earlier, those who could obtain the resources over others would thrive better than others. However, research towards criminal justice assumes that â€Å"power groups determined to use criminal law to advance their own special interested or to impose their moral preferences on others† (Williams McShane, 2014). In layman’s terms, there will be powers within reason to control others based on employment, economic status, social status and other factors that will impede on others. Therefore, competition will always be present within society, and conflict will always occur. However, society dictates that without competition and conflict, then structures of society, including government, would be flawed, and crimes would not be as a individually punishable as it is today. According to Marxist criminology (cited by Williams McShane, 2014), conflict due to limitation of resources and scarcity in distribution of said resources like power can create conflict with those do have power and those who do not. This imbalance stems towards dominance and control and, as a result, dwindles down the middle zone of social hierarchy. Theorists of Conflict Theory Though there are several theorists that benefited from the development of conflict theories, one notable for the most profound change in the theory was Richard Quinney in the 1960s and 1970s. Using his dual degree in social and psychology from Carroll College, his later works in education gathered the â€Å"Lone Ranger† mentality of American values towards his perspective of time (Williams McShane, 2014). His most influential production within the conflict theory is the six propositions of the social reality of crime, where conflict was the product of reaction. Since certain classes react to specific behaviors like criminal behavior, they associate those behaviors to be defined as criminal and subject those behaviors as such for power and gain at a societal level, whether through dominance in numbers of in favor of public appeal. As a result, the divide between the upper and lower classes is strained where the lower classes emulates those around them deviating from the norm a nd subjecting to criminal behavior. Variables of Conflict Theory In the basis of the conflict theory, the variables are more strained towards the individual, but the differences in experimentation differ on a monumental scale. While the dependent variable is the sole individual, the independent variable is redefined to the basis of social status, including finances, employment, and other methods of competition within society. These independent variables also include competition in education, economic status, mental and physical health, and living status (house versus apartment). Because of these implications on the individual and their impacts towards his or her life in society, their life places them in a specific class to where they will be conflicting with others due to how they live their life. Whether they engage in criminal acts as a result is entirely subjective and speculative at best, but any of those factors can assume that criminal behavior can occur. Qualitative Versus Quantitative Based on the information provided by other theorists, the studies involving conflict theory are assumed to be qualitative. For example, under the justifications of conflict theory made by Quinney and Steven Spitzer during the 1970s, Spitzer developed five types of â€Å"problems populations,† where conflicts would most likely occur in society, and the observations he recorded between two different areas of social status presume that no need for control will exist if one group does not impose a threat on the other (Williams McShane, 2014). These observations, including those recorded by Karl Marx over the industrial class, subject nothing to statistical data to support their findings, and the observations by the sole individual create more reliable data to make their findings more conclusive. Conflict Theory: The Good and the Bad While the theory itself is proven to be beneficial to proving common behaviors within society and proving the behaviors associated with social status and social class, it can be commonly proven that the opportunities given to select individuals will lessen and heighten and chances of criminality. With conflict theory, competition and dominance will instill negative behaviors affluent to criminality, stemming criminal behavior and delinquency through any individual based on any factors of socioeconomic status. However, the theory assumes that all people within a specific class will compete and lead to criminal behavior. For example, the entirety of the lower class will dwell into crime because of the lack of resources the upper class have that the lower class need creates conflict between the two, proving Quinney’s proposal as earlier stated. Though this does prove criminal behavior within conflict, it does not substantiate and validate the findings of all forms of conflict. It only assumes conflict as a common predictor to all forms of crime rather than proving a certain variable can be the first step to all criminality. Instead, the form translates to the socioeconomic status as an overgeneralized example, therefore, causing reliability of all statistics to be flawed. Macro-theory Versus Micro-theory Based on the information provided earlier, this would be classified as a micro theory. The study of social struggles between the poor and the middle to upper class. The disparity in resources or social status causes the greatest conflicts. The laws are implemented to favor the rich, and leave the poor at a distinct disadvantage, forcing them to remain where they are without any distinct change in their standards of living. Personal Reflection I wholeheartedly agree with the main idea of this theory. Conflicts in society are inevitable. People, in general, have aspirations and ambitions, and when others with a different philosophy or mindset disagree, this causes friction or conflict. In some instances, a person’s ambition can spiral out of control, causing the ambition to take a desperate edge and become something negative everywhere the initial intentions are noble. Another point of this theory I agree with is the rich or affluent have the upper hand in society. They have the money, which translates into power, and results in them having a profound advantage over the poor. Money gets you notoriety, political power, and, at times, can buy them justice. Despite the influence of class with money, money does not guarantee class. It simply gives you better opportunities. There are just as many poor people with class, integrity and honesty as the privileged. Policy Implications Because many areas within society are crippled due to the introduction of conflict theory, there are various policy implications that can complement and prevent certain behaviors from occurring. As stated in earlier papers, one common solution to reducing crime and any form of recidivism is the factor of minimum wage. By increasing minimum wage state-wide, more jobs are created and higher opportunities of living are created for the lower and middle class. This would constitute a better standard of living pursuant of the American Dream, but there are issues. Since people are already assumed to be competitive, the works of specific individuals in certain classes, including the upper class, will still create conflict. For example, in the sake of unions, the beginning of unions was to give workers some rights and affordable wages to wear the workers could provide for their families and have sustainable living. Over time, the workers would want more and more until the owners would make co sts to their own lives and the workers are no longer in control. The workers’ competitiveness and willpower to ask for more consistently causes instability between the working class (proletariat) and the owners (bourgeoisie). There has been speculation to whether increasing wages would help, but inflation would result for standards of living because competition will exist through dominance and control. However, what if wages were made a set limit regardless of education or status, and set based on employment. One person is paid ten dollars an hour as a cashier for McDonalds while another person is paid 30 dollars an hour as a police officer to ensure the protection of the communities he is sworn to protect and serve. Competition with wages will still occur as well as conflict due to the bias of employment and stereotypical bias. Therefore, wages changing isn’t beneficial to society, but it assists those as a readily available solution to react quickly and only in the moment to assist. At the same effect, another possible solution towards conflict theory in society is providing free education for all citizens, regardless of economic status. In Germany today, all colleges have been made free for tuition, which may lead most American citizens who have usable visas and are seeking further education to head overseas for an easily affordable education (Salles, 2014). Because of this drastic change in policy, the United States could implement this, but the system of government seems too controlling towards the middle and lower class to let anything happen to their puppets in the masquerade of life they ordain and manipulative for the upper class to gain. Since most students attending colleges in the United States are toppling with debt due to high tuition rates, it seems more reasonable for governments to be conflict with one another based on public policy, but the individuals are given better opportunities between the two as a means for a higher standard of living. References Salles, J.M. (2014). â€Å"This Country Just Abolished College Tuition Fees.† Thinkprogress.org. Retrieved from http://thinkprogress.org/education/2014/10/01/3574551/germany-free-college-tuition/ Williams III, F.P. McShane, M.D. (2014). Criminological Theory (6th Ed.). Upper Saddle River: Pearson/Prentice Hall.

Comparing the Rich versus the Poor Essay -- Poverty

Rich v. Poor Take a moment and picture a child half naked in the streets. His body has been harshly neglected. Little to no calf muscles exist. His ribs are plainly countable. One, two, three up his left side. You can do the same to his right. Malnutrition only vaguely begins to describe his condition. The worst of anorexia doesn’t even compare to this child’s inhumane state. As for shelter, he lives in a dilapidated hut. Food is a luxury, as the child may be fed only three or four times a week. He’s expected to die by the age of five due to severe malnutrition and disease. This is the grim portrait of an Ethiopian child in absolute poverty. His life doesn’t allow for the basic essentials of food, shelter, or clothing. In today’s world poverty is not only viewed in terms of average income/wealth, but as the lower end of distribution regarding income, education, health accessibility, nutrition, productivity, participation in politics, etc. Thus, poverty is defined as the â€Å"economic condition in which people lack sufficient income to obtain certain minimal levels of health services, food, housing, clothing, and education generally recognized as necessary to ensure an adequate standard of living† (Funk & Wagnall 1). Adequate, however, depends on the standard of living for each country. There are two different types of poverty today—relative and absolute. Nearly half of a billion people live in relative poverty—â€Å"meaning that some citizens are poor, relative to the wealth enjoyed by their neighbors† (Singer 218). To put these figures in terms one can relate to, it’s estimated that about 10% of human life resides in relative poverty. This is a substantial amount, but their condition is quite well ... ...ay, â€Å"prevent something very bad from happening, without [thereby] sacrificing anything of comparable moral significance†¦Ã¢â‚¬  (Singer 229), and we should. Works Cited * Hardin, Garret. â€Å"Living on a Lifeboat.† Contemporary Moral Problems. American Institute of Biological Sciences, 1974: 246-257. * â€Å"Poverty.† Funk & Wagnall’s New Encyclopedia. 1992: 1-2. * Quadrini, Vincenzo.; Rà ­os-Rull, Josà ©-Và ­ctor. â€Å"Understanding the U.S. Distribution of Wealth.† http://newfirstsearch.oclc.org * Federal Reserve Bank of Minneapolis Quarterly Review v. 21 no2. Spring. 1997: 22-36. * Singer, Peter. â€Å"Rich and Poor.† Practical Ethics. 2nd ed. Cambridge: Cambridge University Press, 1993: 218-246. * Speth, James Gustave. â€Å"The Plight of the Poor: The Unites States Must Increase Development Aid.† Foreign Affairs v. 78 no3. May/June. 1999: 1-3.

In Favor of the Network Cap :: Internet Technology Essays

In Favor of the Network Cap Iowa State’s internet administrators had a problem: several computers around campus had been being used as Internet servers for illegitimate data distribution, and these select computers were using a severe amount of bandwidth on the ISU student network. The undeniable fact is that these are students illegally serving copyrighted software and media to people outside the ISU network, and they are taking up an extreme proportion of the network’s available bandwidth. Although this abuse had not yet caused consistent detrimental network problems for many users, the problem was getting worse, and AIT’s network cap decision has halted it. AIT’s 500 megabyte network cap is justified. Warez servers on the ISU campus send out a huge amount of data and slow the network down. We should be greedy about our network speed because our tuition is paying for ISU’s internet connection. It is true that an alternative method, such as filters based on complex data rate monitoring algorithms, might do a better job preventing the warez servers network abuse, and keep many intensive users from protest. But such measures are likely unfeasible, due to limitations of AIT’s network software, and time limitations of AIT network analysts. If the 500 meg cap does indeed cause real problems for a number of legitimate users, investigation of these other methods can be pursued. The 500 megabyte cap was a good and timely solution. Those who disagree with the cap argue that it would affect their legitimate network usage, such as Quake 3 game servers, or people with websites that they serve from their own computers. Instances where these users will actually peak 500 megs in a day are rare, however. Even a moderately trafficked user web site might never send 100 megabytes a day; the simple reality is that 500 megs per day is, 99% of the time, only surpassed when a user is illegally serving a large amount of data such as music, movies, retail software, or pornography to a large audience. This is precisely the user that clogs the bandwidth for those of us who need it to get work done, and this is precisely the type of network abuse that the network cap targets.

Analysis of Hazlitts Article on Travel :: Literary Analysis Travel Essays Papers

Analysis of Hazlitt's Article on Travel Hazlitt's article on travel advocates the benefits of solo travel within one's own country. His affection for travel is strong. He calls going on a journey "one of the pleasantest things in the world". Hazlitt stresses that solitude while on a journey is a must, saying "nature is company enough for me", and "I am never less alone than when alone". Hazlitt insists that sharing in the experience of nature with a companion takes away from the sensory experience of it. He asserts bluntly: "I cannot see the wit of walking and talking at the same time". He believes conversation distracts from the scenery, and that nature does not need to be discussed, only experienced. To tale about the scene while experiencing it diminishes it and takes away from its immediate beauty. Scenery is not to be negotiated. Everyone will have their own unique experience of nature, and since each experience is personal it is futile to compare experiences. Hazlitt says: "The continual comparing of notes interferes with the involuntary impression of things upon the mind, and hurts the sentiment". His view opposes that of Alphonse Frankenstein, who urges Victor to take a family tour of the Chamounix, insisting that companionship in the experience compounds its remedial value. But Hazlitt seeks freedom from fellow men when he journeys. He says "the soul of a j ourney is liberty...to think, feel, do, just as one pleases". When experiencing nature in solitude, Hazlitt is able to appreciate it to its full extent by becoming one with nature. He says "when i am in the country i wish to vegetate like the country". A journey should be a time of freedom and peace, away from all things associated with city life. When travelling alone you are " a creature of the moment...free of all ties". A journey can provide "a little breathing space" to refresh and revitalize a person. When on a journey, Hazlitt says he begins "to feel, think and be myself again". He finds joy in living while in nature: "Give me the clear blue sky over my head, and the green turf beneath my feet...I laugh, I run, I leap, I sing for joy". Hazlitt's language describes the experience as being cathartic, like a return to the innocence of childhood. Hazlitt says the freedom found in nature comes from being away from people, and allowing the mind to rest.

Lesson Vocabulary

They related one Of the disease Symptoms such as memory loss to her forgetting to take out the trash. Menopause- the time of natural cessation of menstruation. On the popular television show 19 kids and counting, the mother had went to her doctors office questioning whether or not she was able to have more children. The doctor had went trough numerous questions, one of which included whether she has gone through menopause as this would indicate that her body is not able to carry any more children.Cross-sectional study-a study in which people Of different ages are compared with one another. As was listening to the radio one day, there was an advertisement looking for people aged 10-65, in order for them to compare how the brain reacts to different stimuli as the brain ages. This is an example of a cross-sectional study as there is a group of people within a large range of ages in order for them to be compared to one another. Institutional study- research on which the same people are r estudied and retested over a long period of time.A study in which children who are given medication to treat a disease, and are tested then and every five years in order to see the development with the ewe drug(whether it is working,etc) is an example of a longitudinal study as the same people are being tested for the medication and are having to be retested in order to reassure the medication is working. Adolescence- the transition period from childhood to adulthood, extended from puberty to independence.When conversing with a coworker who is above the age of twenty five and is living on their own, settled down with a family, and has a stable job, you are more than likely to consider this individual to have gone through adolescence as they are now quite independent and have had many years after starting puberty. Primary sex characteristics- the body structures that make sexual reproduction possible. If a female were to lack ovaries, she would be lacking a primary sex characteristic , as without ovaries, natural reproduction is impossible.Secondary sex characteristics- non-reproductive sexual traits, such as female breasts and hips, male voice quality, and body hair. While working down the street, you notice a striking young man, with a trimmed beard, well dressed, and a low voice. You are attracted to his secondary sex characteristics as you like his beard, which is a secondary sex characteristic, as well as his deep voice. Social clock- the culturally preferred timing of social events such as marriage, parenthood, and retirement.During the renaissance, if you were not married by the age of 15, you were considered to be a witch, as only one of the dark side would have this flaw. This can be seen as an extreme formation of a social clock as they believe one must be married by a certain age. Menarche, the first menstrual period. When a child enters the third grade many times they are asked if they would like to take a sex deed class. In this class they will disc uss numerous topics, one which may include menarche as many females will be unaware of this at this GE in order to educate the young females that it is just a sign of their bodies functionally properly.Fluid intelligence- our ability to reason speedily and abstractly. Having fluid intelligence is quite necessary as a teenager because decisions are made quickly and you must be able to sort the complications as well as the advantages Of doing an activity. Crystallized intelligence- our accumulated knowledge and verbal skills. If one were to speak of a book they read last year and discuss what occurred in the book, they are using crystallized intelligence as they are pulling information from a later date.